Structural Biologist (cryo-EM), Biophysicist, Biochemist

My interests are in the fundamental understanding of protein macromolecular complexes and the development of methods for doing this. I have framed this in the context of membrane interacting and remodelling proteins in cellular trafficking. Recently, I have become interested in nucleotide-protein interactions and am pursuing avenues that unite these interests. 

I prefer to collaborate heavily and have worked on structural projects concerning metabolite and nitric oxide sensing, protein phosphorylation, transmembrane neuronal gap junctions, gene editing and genomic maintenance. 

Complexes previously inaccessible to study by X-ray crystallography and too large for NMR may now have their high resolution structures determined by cryo-EM. I am excited to be part of the advancement in our understanding of such systems and day-to-day immersing in big computation, enabling efficient data collection, structural interpretation and biochemistry. In the future I hope to bridge the gap between observations made at cellular level and from high resolution structural biology.

I currently work as a Senior Investigator Scientist at the MRC London Institute of Medical Sciences (LMS).