My interests are in the characterisation of self-assembling protein systems and the development of cutting edge methods for doing this. Recently I have been framing this in the context of membrane interacting and remodelling proteins. I have a particular interest in cryo electron microscopy, computational image processing and single molecule methods for structure determination.

The link between molecular architecture, assembly and macromolecular morphology is fascinating. Understanding structurally and mechanistically how multimerisation produces physiologically important assemblies develops our understanding of normal and pathological processes. Further, this research will advance our ability to manipulate and even design such systems.